Both of Dr. Nyland's research areas are related to the immunotoxic effects of metals exposure. One focus relates to epidemiological studies that examine the effects of mercury on biomarkers of immune modulation, and in vitro studies to probe the mechanisms of these effects. The other area relates to the utilization of in vivo mouse models of disease (autoimmune myocarditis, type-2 diabetes, and obesity) to explore the impacts of mercury and arsenic exposure on mechanisms of disease progression and severity.
Any SU student who works with Dr. Nyland in her lab will begin with in vitro studies on the effects of environmental toxicants on the immune system. They will also examine outcomes such as: cytokine profile; immune-related gene expression; and epigenetic changes in terms of genomic DNA methylation.